Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion and insertion mutations in short tandem repeats in the coding regions of human genes.

European journal of human genetics : EJHG - 1 Jan 1995

Darvasi A, Kerem B

Abstract excerpt

In vitro studies in bacterial, yeast and eukaryotic systems have demonstrated the existence of deletion and insertion 'hot-spots' involving repetitive sequences. Slipped-strand mispairing (SSM) has been suggested to be the mechanism involved. Progress in human molecular genetics has allowed the identification of many mutations causing diseases. Analysis of sequences involved in these mutations provides an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA Mutational Analysis
Share to Membrane Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutagenesis, Insertional

Share to Mutation

Share to Repetitive Sequences, Nucleic Acid

Share to Sequence Deletion

Source

Identifiers

PMID: 7539330
DOI: 10.1159/000472269

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion and insertion mutations in short tandem repeats in the coding regions of human genes.PMID 7539330Read ↗

Short tandem repeats in human exons: a target for disease mutations.Semantic proximity Read ↗

Distinct sequence features underlie microdeletions and gross deletions in the human genome.Semantic proximity Read ↗

Distinct sequence features underlie microdeletions and gross deletions in the human genomeSemantic proximity Read ↗

The rates and patterns of deletions in the human factor IX gene.Semantic proximity Read ↗

High Frequency of Pathogenic Rearrangements in SPG11 and Extensive Contribution of Mutational Hotspots and Founder Alleles.Semantic proximity Read ↗

Hypermutability of genes in Homo sapiens due to the hosting of long mono-SSR.Semantic proximity Read ↗

Disease-causing mutations in the human genome.Semantic proximity Read ↗

Mutation patterns of amino acid tandem repeats in the human proteome.Semantic proximity Read ↗

Short Tandem Repeats of Human Genome Are Intrinsically Unstable in Cultured Cells <i>in vivo</i>Semantic proximity Read ↗

Slipped strand DNA structuresSemantic proximity Read ↗

Genomic rearrangements in the CFTR gene: extensive allelic heterogeneity and diverse mutational mechanisms.Semantic proximity Read ↗

Insertions, substitutions, and the origin of microsatellites.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.