Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insights into the genetic and molecular basis of primary pulmonary hypertension.

Pediatric research - 1 Jun 2003

Trembath Richard C, Harrison Rachel

Abstract excerpt

The pathogenesis of primary pulmonary hypertension (PPH) remains poorly understood. Molecular genetic studies have identified that mutations within the gene BMPR2 on the long arm of chromosome 2 underlie familial PPH. This review explores the significance of the PPH gene identification and examines additional genetic determinants, emphasizing the immediate implications for assessment and management of patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Morphogenetic Protein Receptors, Type II
Share to BMPR2 gene
Share to Genetic Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension, Pulmonary

Share to Mutation

Share to Protein Serine-Threonine Kinases

Share to Transforming Growth Factor beta

Source

Identifiers

PMID: 12621102
DOI: 10.1203/01.PDR.0000061565.22500.E7

Genes

BMPR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insights into the genetic and molecular basis of primary pulmonary hypertension.PMID 12621102Read ↗

The Genetics of Pulmonary Arterial Hypertension in the <i>Post‐BMPR2</i> EraSemantic proximity Read ↗

Gene symbol: BMPR2. Disease: Pulmonary hypertension, primary.Semantic proximity Read ↗

Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension.Semantic proximity Read ↗

Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects.Semantic proximity Read ↗

Genetics of pulmonary arterial hypertension.Semantic proximity Read ↗

Heritable Forms of Pulmonary Arterial HypertensionSemantic proximity Read ↗

Genetics and mediators in pulmonary arterial hypertension.Semantic proximity Read ↗

'There and Back Again'-Forward Genetics and Reverse Phenotyping in Pulmonary Arterial Hypertension.Semantic proximity Read ↗

Genes in pediatric pulmonary arterial hypertension and the most promising BMPR2 gene therapySemantic proximity Read ↗

Pulmonary arterial hypertension: insights from genetic studies.Semantic proximity Read ↗

The genetics of pulmonary arterial hypertension.Semantic proximity Read ↗

The genetic basis of pulmonary arterial hypertension.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.