Article
Evidence for divergence of DNA copy number changes in serous, mucinous and endometrioid ovarian carcinomas.
British journal of cancer - 1 Jan 1997
Tapper J, Bützow R, Wahlström T, Seppälä M, Knuutila S
Abstract excerpt
Comparative genomic hybridization was applied to detect and map changes in DNA copy number in 24 well or moderately differentiated epithelial ovarian carcinomas (eight serous, eight mucinous and eight endometrioid carcinomas). Twenty-three of the 24 tumours showed changes in DNA copy number in one or several regions (median 4, range 1-17). Gains were more frequent than losses (ratio 1.6:1.0). The most frequent...
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