Article
Correlations between c-myc gene copy-number and clinicopathological parameters of ovarian tumours.
European journal of cancer (Oxford, England : 1990) - 1 Mar 2006
Dimova I, Raitcheva S, Dimitrov R, Doganov N, Toncheva D
Abstract excerpt
The objective of this study was to investigate increases in c-myc gene copy-number in ovarian tumours, and to analyze their correlations with clinicopathological parameters. Here we applied FISH on TMA (tissue microarrays) containing 507 ovarian tumour samples from different malignancy, histology, stage and grade. Overall, we found high frequency for c-myc copy-number increases (38.5%) in ovarian cancers: 22.1%...
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