Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Amplified genes may be overexpressed, unchanged, or downregulated in cervical cancer cell lines.

PloS one - 1 Jan 2012

Vazquez-Mena Oscar, Medina-Martinez Ingrid, Juárez-Torres Eligia, Barrón Valeria, Espinosa Ana, Villegas-Sepulveda Nicolás, Gómez-Laguna Laura, Nieto-Martínez Karem, Orozco Lorena, Roman-Basaure Edgar, Muñoz Cortez Sergio, Borges Ibañez Manuel, Venegas-Vega Carlos, Guardado-Estrada Mariano, Rangel-López Angélica, Kofman Susana, Berumen Jaime

Abstract excerpt

Several copy number-altered regions (CNAs) have been identified in the genome of cervical cancer, notably, amplifications of 3q and 5p. However, the contribution of copy-number alterations to cervical carcinogenesis is unresolved because genome-wide there exists a lack of correlation between copy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Aberrations
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Amplification

Share to Gene Expression Profiling

Share to Gene Expression Regulation, Neoplastic

Share to Genome, Human

Share to Molecular Sequence Annotation

Share to Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 22412903
DOI: 10.1371/journal.pone.0032667
PMCID: PMC3296745

Genes

AHRR
DAP
ECT2
PARP1
PDCD6
TNFSF10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22412903-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Amplified genes may be overexpressed, unchanged, or downregulated in cervical cancer cell lines.PMID 22412903Read ↗

Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha.Semantic proximity Read ↗

Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumorsSemantic proximity Read ↗

Chromosomal amplifications, 3q gain and deletions of 2q33-q37 are the frequent genetic changes in cervical carcinomaSemantic proximity Read ↗

Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer.Semantic proximity Read ↗

Integrative Genomic Approaches in Cervical Cancer: Implications for Molecular PathogenesisSemantic proximity Read ↗

Transcriptional effects of copy number alterations in a large set of human cancers.Semantic proximity Read ↗

Microarray comparative genomic hybridization detection of chromosomal imbalances in uterine cervix carcinomaSemantic proximity Read ↗

Genetic alterations in cervical carcinomas: Frequent low‐level amplifications of oncogenes are associated with human papillomavirus infectionSemantic proximity Read ↗

Gene amplification in cancer.Semantic proximity Read ↗

A compendium of Amplification-Related Gain Of Sensitivity (ARGOS) genes in human cancerSemantic proximity Read ↗

Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gainsSemantic proximity Read ↗

Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: potential role in progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.