Article
The low density lipoprotein receptor gene family. Differential expression of two alpha2-macroglobulin receptors in the brain.
The Journal of biological chemistry - 27 Nov 1998
Stockinger W, Hengstschläger-Ottnad E, Novak S, Matus A, Hüttinger M, Bauer J, Lassmann H, Schneider W J, Nimpf J
Abstract excerpt
LR7/8B is a member of the low density lipoprotein receptor gene family that is specifically synthesized in the brain. Here we have functionally expressed in 293 cells the splice variant harboring eight ligand binding repeats (LR8B). As assessed by confocal microscopy, the expressed receptor is lo...
Topics
- Alternative Splicing
- Animals
- Binding Sites
- Brain
- Cell Line
- Chickens
- Genetic Variation
- Humans
- Immunohistochemistry
- Kinetics
- Low Density Lipoprotein Receptor-Related Protein-1
- Multigene Family
- Rats
- Receptors, Immunologic
- Receptors, LDL