Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors.

Cancer research - 15 Jun 1997

Xie J, Johnson R L, Zhang X, Bare J W, Waldman F M, Cogen P H, Menon A G, Warren R S, Chen L C, Scott M P, Epstein E H

Abstract excerpt

Patients with basal cell nevus syndrome have a high incidence of multiple basal cell carcinomas, medulloblastomas, and meningiomas. Because somatic PATCHED (PTCH) mutations have been found in sporadic basal cell carcinomas, we have screened for PTCH mutations in several types of sporadic extracut...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Heterozygote

Share to Membrane Proteins

Share to Mutation

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 9192811

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9192811-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors.PMID 9192811Read ↗

Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system.Semantic proximity Read ↗

Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched.Semantic proximity Read ↗

Identification of PATCHED mutations in medulloblastomas by direct sequencing.Semantic proximity Read ↗

Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32.Semantic proximity Read ↗

Identification of Mutations in the Human PATCHED Gene in Sporadic Basal Cell Carcinomas and in Patients with the Basal Cell Nevus SyndromeSemantic proximity Read ↗

Mutations in the human homologue of the Drosophila patched gene in esophageal squamous cell carcinoma.Semantic proximity Read ↗

The spectrum of patched mutations in a collection of Australian basal cell carcinomas.Semantic proximity Read ↗

Mutations in the human homologue of Drosophila patched (PTCH) in basal cell carcinomas and the Gorlin syndrome: different in vivo mechanisms of PTCH inactivation.Semantic proximity Read ↗

Mutations in the human homologue of Drosophila patched in Japanese nevoid basal cell carcinoma syndrome patients.Semantic proximity Read ↗

UV-specific mutations of the human patched gene in basal cell carcinomas from normal individuals and xeroderma pigmentosum patients.Semantic proximity Read ↗

The normal patched allele is expressed in medulloblastomas from mice with heterozygous germ-line mutation of patched.Semantic proximity Read ↗

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.