Article
[Malignant hyperthermia as a complication of anesthesia: predisposition is hereditary].
Nederlands tijdschrift voor geneeskunde - 29 Mar 1997
Snoeck M M, Gielen M J, Sengers R C, Padberg G W, Iles D E, Booij L H
Abstract excerpt
The frequency of malignant hyperthermia in the Netherlands is about 1 in 200,000 anaesthesias. Five times a year, an anaesthetic procedure will be complicated by a malignant hyperthermic metabolic disturbance, which can cause death if treatment is not instituted rapidly, by the administration of...
Topics
- Calcium Channels
- Calmodulin-Binding Proteins
- Genes, Dominant
- Genetic Predisposition to Disease
- Humans
- Malignant Hyperthermia
- Muscle Proteins
- Point Mutation
- Ryanodine Receptor Calcium Release Channel