Malignant hyperthermia susceptibility, an autosomal dominant disorder?

doi:10.1111/j.1399-0004.1997.tb02492.x

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Article

Malignant hyperthermia susceptibility, an autosomal dominant disorder?

Clinical genetics - 1 Jun 1997

Fagerlund T H, Islander G, Ranklev Twetman E, Berg K

Abstract excerpt

A large series of Swedish nuclear families, in which malignant hyperthermia (MH) reactions had occurred during anaesthesia, have been examined with respect to malignant hyperthermia susceptibility. In vitro contracture tests (IVCT) of muscle strips were conducted to diagnose MH status. Included i...

Topics

Adolescent
Adult
Caffeine
Calcium Channels
Child
Child, Preschool
Female
Genes, Dominant
Genetic Predisposition to Disease
Halothane
Humans
Male
Malignant Hyperthermia
Muscle Contraction
Muscle Proteins
Muscle, Skeletal
Mutation
Ryanodine Receptor Calcium Release Channel

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