Article
[Diagnosis of susceptibility for malignant hyperthermia using in-vitro muscle contraction testing in Switzerland].
Schweizerische medizinische Wochenschrift - 20 Apr 1991
Urwyler A, Censier K, Seeberger M D, Drewe J, Rothenbühler J M, Frei F
Abstract excerpt
Malignant hyperthermia is a potentially fatal pharmacogenetic disorder triggered by volatile anesthetics (halothane, enflurane, isoflurane) and/or succinylcholine. The inheritance of malignant hyperthermia susceptibility is thought to be autosomal dominant and the incidence could be as high as 1:10,000. The only generally accepted diagnostic method at present involves a muscle biopsy followed by in-vitro...
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