Exclusion of the 13-kDa rapamycin binding protein gene (FKBP2) as a candidate gene for multiple endocrine neoplasia type 1.

doi:10.1007/BF00208976

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Exclusion of the 13-kDa rapamycin binding protein gene (FKBP2) as a candidate gene for multiple endocrine neoplasia type 1.

Human genetics - 1 Apr 1995

Grimmond S, Weber G, Larsson C, Walters M, Teh B, Shepherd J, Nordenskjold M, Hayward N

Abstract excerpt

The MEN1 gene is considered to be a tumour suppressor gene and has been localised to a 1-Mb region of 11q13.1. In this study, we report the physical localisation of the 13-kDa FK506 and rapamycin binding protein gene (FKBP2) to the cosmid marker D11S750, which is located inside the MEN1 region of non-recombination. The product of this gene is involved in signal transduction and is thus a candidate cell growth...

Topics

Base Sequence
Carrier Proteins
Chromosome Mapping
Cosmids
DNA, Neoplasm
DNA-Binding Proteins
Genes, Tumor Suppressor
Genetic Markers
Heat-Shock Proteins
Humans
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Weight

Multiple Endocrine Neoplasia Type 1

Mutation

Polymerase Chain Reaction

Polymorphism, Single-Stranded Conformational

Tacrolimus

Tacrolimus Binding Proteins

Source

Open in PubMed

Identifiers

PMID: 7535744
DOI: 10.1007/BF00208976

Genes

MEN1
FKBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7535744-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Exclusion of the 13-kDa rapamycin binding protein gene (FKBP2) as a candidate gene for multiple endocrine neoplasia type 1.PMID 7535744Read ↗

Genetic screening to identify the gene carrier in Italian and German kindreds affected by multiple endocrine neoplasia type 1 (MEN 1) syndrome.Semantic proximity Read ↗

Concomitant deletions of tumor suppressor genes <i>MEN1</i> and <i>AIP</i> are essential for the pathogenesis of the brown fat tumor hibernomaSemantic proximity Read ↗

The search for the MEN1 gene. The European Consortium on MEN-1.Semantic proximity Read ↗

Examination of chromosome 7p22 candidate genes RBaK, PMS2 and GNA12 in familial hyperaldosteronism type II.Semantic proximity Read ↗

Fine mapping of the MLK-3 gene within 11q13 and its exclusion as the MEN1 susceptibility gene.Semantic proximity Read ↗

The human HNP36 gene is localized to chromosome 11q13 and produces alternative transcripts that are not mutated in multiple endocrine neoplasia, type 1 (MEN I) syndrome.Semantic proximity Read ↗

The gene for the peroxisomal targeting signal import receptor (PXR1) is located on human chromosome 12p13, flanked by TPI1 and D12S1089.Semantic proximity Read ↗

A new DNA marker (D10S94) very tightly linked to the multiple endocrine neoplasia type 2A (MEN2A) locus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.