Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association.

doi:10.1016/s0014-5793(97)00300-1

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Article

Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association.

FEBS letters - 5 May 1997

Wise A, Parenti M, Milligan G

Abstract excerpt

Wild-type and palmitoylation defective mutants of the murine G protein G11alpha were transfected into HEK293 cells. Wild-type G11alpha was membrane associated, Cys9Ser Cys10Ser G11alpha was present in the soluble fraction whilst both Cys9Ser G11alpha and Cys10Ser G11alpha were distributed between...

Topics

Animals
Cell Line
Enzyme Activation
GTP-Binding Proteins
Humans
Mice
Mutation
Palmitic Acids
Phosphoric Diester Hydrolases
Rats
Receptors, Thyrotropin-Releasing Hormone
Thyrotropin-Releasing Hormone
Transfection

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