Article
A dtsR gene-disrupted mutant of Brevibacterium lactofermentum requires fatty acids for growth and efficiently produces L-glutamate in the presence of an excess of biotin.
Biochemical and biophysical research communications - 8 May 1997
Kimura E, Abe C, Kawahara Y, Nakamatsu T, Tokuda H
Abstract excerpt
A dtsR gene encoding a homolog of the beta subunit of some biotin-containing enzymes suppresses a detergent-sensitive mutation of Brevibacterium lactofermentum (E. Kimura et al., 1996, Biosci. Biotech. Biochem. 60, 1565-1570), which has been used for the fermentative production of L-glutamate. Wh...
Topics
- Bacterial Proteins
- Biotin
- Blotting, Southern
- Blotting, Western
- Brevibacterium
- Detergents
- Fatty Acids
- Genes, Bacterial
- Genes, Suppressor
- Glutamic Acid
- Mutagenesis, Site-Directed
- Mutation
- Oleic Acid
- Palmitic Acid
- Plasmids
- Restriction Mapping