Article
A role for HDJ-2/HSDJ in correcting subnuclear trafficking, transactivation, and transrepression defects of a glucocorticoid receptor zinc finger mutant.
Molecular biology of the cell - 1 May 1997
Tang Y, Ramakrishnan C, Thomas J, DeFranco D B
Abstract excerpt
All steroid receptors possess a bipartite nuclear localization signal sequence (NLS) that localizes within the second zinc finger of their DNA-binding domain. Fine-structure mapping of the rat glucocorticoid receptor (rGS) NLS identified a composite signal composed of three distinct proto-NLSs that function effectively when present in unique pairs. At least one of the rGR proto-NLSs appears to influence receptor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
