Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common and variant gene fusions predict distinct clinical phenotypes in rhabdomyosarcoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 May 1997

Kelly K M, Womer R B, Sorensen P H, Xiong Q B, Barr F G

Abstract excerpt

PURPOSE: We evaluated the clinical features of the common PAX3-FKHR and variant PAX7-FKHR gene fusions observed in rhabdomyosarcoma. PATIENTS AND METHODS: Reverse-transcriptase polymerase chain reaction (RT-PCR) assays were used to detect the gene fusions in 34 cases of rhabdomyosarcoma. Clinical data were obtained retrospectively and compared with the molecular results. RESULTS: The PAX3-FKHR and PAX7-FKHR gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Child
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cloning, Molecular

Share to DNA-Binding Proteins

Share to Homeodomain Proteins

Share to Infant

Share to Neoplasm Proteins

Source

Identifiers

PMID: 9164192
DOI: 10.1200/JCO.1997.15.5.1831

Genes

PAX7
PAX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common and variant gene fusions predict distinct clinical phenotypes in rhabdomyosarcoma.PMID 9164192Read ↗

PAX3-FKHR and PAX7-FKHR Gene Fusions Are Prognostic Indicators in Alveolar Rhabdomyosarcoma: A Report From the Children’s Oncology GroupSemantic proximity Read ↗

Identification of a PAX-FKHR Gene Expression Signature that Defines Molecular Classes and Determines the Prognosis of Alveolar RhabdomyosarcomasSemantic proximity Read ↗

Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors.Semantic proximity Read ↗

Detection of the PAX3-FKHR fusion gene in paediatric rhabdomyosarcoma: a reproducible predictor of outcome?Semantic proximity Read ↗

Fusions Involving PAX and FOX Genes in the Molecular Pathogenesis of Alveolar Rhabdomyosarcoma: Recent AdvancesSemantic proximity Read ↗

Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma.Semantic proximity Read ↗

FOXO1-FGFR1 fusion and amplification in a solid variant of alveolar rhabdomyosarcoma.Semantic proximity Read ↗

Co-expression of alternatively spliced forms of PAX3, PAX7, PAX3-FKHR and PAX7-FKHR with distinct DNA binding and transactivation properties in rhabdomyosarcoma.Semantic proximity Read ↗

The role of chimeric paired box transcription factors in the pathogenesis of pediatric rhabdomysarcoma.Semantic proximity Read ↗

Genome-Wide Identification of PAX3-FKHR Binding Sites in Rhabdomyosarcoma Reveals Candidate Target Genes Important for Development and CancerSemantic proximity Read ↗

Alveolar rhabdomyosarcoma: is the cell of origin a mesenchymal stem cell?Semantic proximity Read ↗

Fusion Gene–Negative Alveolar Rhabdomyosarcoma Is Clinically and Molecularly Indistinguishable From Embryonal RhabdomyosarcomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.