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Article

Effects of pleiotrophic mutations, degUh and spoOA, on the production of foreign proteins using the heterologous secretion system of Bacillus subtilis.

Molecules and cells - 30 Apr 1997

Kim S I, Choi J W, Lee S Y

Abstract excerpt

To elevate the production of foreign target proteins using a heterologous protein secretion system of Bacillus subtilis, two different pleiotrophic mutations, degUh for increase of transcriptional level of target genes and spoOA for reduction of extracellular protease activity of a host strain were introduced, respectively. The productivities of three differently originated enzymes, beta-lactamase, streptokinase...

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PMID: 9163726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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