Signal transduction pathway controlling synthesis of a class of degradative enzymes in Bacillus subtilis: expression of the regulatory genes and analysis of mutations in degS and degU.

Abstract excerpt

The rates of synthesis of a class of both secreted and intracellular degradative enzymes in Bacillus subtilis are controlled by a signal transduction pathway defined by at least four regulatory genes: degS, degU, degQ (formerly sacQ), and degR (formerly prtR). The DegS-DegU proteins show amino acid similarities with two-component procaryotic modulator-effector pairs such as NtrB-NtrC, CheA-CheY, and EnvZ-OmpR. By...

Topics

• Amino Acid Sequence
• Bacillus subtilis
• Base Sequence
• Cloning, Molecular
• Codon
• Escherichia coli
• Gene Expression Regulation, Bacterial
• Genes, Regulator
• Genotype
• Hydrolases