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Article

p53, mutation frequency and apoptosis in the murine small intestine.

Oncogene - 1 May 1997

Clarke A R, Howard L A, Harrison D J, Winton D J

Abstract excerpt

Normal function of the p53 gene is integral to the cellular response to genotoxic stress. One prediction arising from this is that p53 deficiency results in an increased mutation frequency. However, limited evidence has been produced in support of this idea. In order to further investigate the in vivo role of p53 in surveillance against mutation, and particularly to address the significance of p53-dependent...

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Identifiers

PMID: 9160880
DOI: 10.1038/sj.onc.1201040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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