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Article

[Mechanism on androgen-independent progression of prostate cancer].

Nihon rinsho. Japanese journal of clinical medicine - 1 May 1997

Shimazaki J, Akakura K, Furuya Y, Ito H

Abstract excerpt

Eighty percent of prostate cancer with metastasis respond to androgen ablasion, showing initial androgen-sensitive growth. However, more than half of responders gradually loses dependency up to 5 years. Animal experiments reveal that loss of androgen sensitivity is attributable to complex reasons...

Topics

Androgen Antagonists
Androgens
Animals
Disease Progression
Drug Resistance, Neoplasm
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor
Humans
Male
Mutation
Orchiectomy
Prostatic Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Androgen

Tumor Cells, Cultured

Source

Identifiers

PMID: 9155166

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9155166-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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