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Article

A homolog of interleukin-10 is encoded by the poxvirus orf virus

1 Jun 1997

Abstract excerpt

A gene encoding a polypeptide with homology to interleukin-10 (IL-10) has been discovered in the genome of orf virus (OV) strain NZ2, a parapoxvirus that infects sheep, goats, and humans. The predicted polypeptide sequence shows high levels of amino acid identity to IL-10 of sheep (80%), cattle (75%), humans (67%), and mice (64%), as well as IL-10-like proteins of Epstein-Barr virus (63%) and equine herpesvirus...

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PMID: 9151886
DOI: 10.1128/jvi.71.6.4857-4861.1997

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