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Temporal expression classes and functions of vaccinia virus and mpox (monkeypox) virus genes

20 Mar 2025

Abstract excerpt

Poxviruses comprise pathogens that are highly pathogenic to humans and animals, causing diseases such as smallpox and mpox (formerly monkeypox). The family also contains members developed as vaccine vectors and oncolytic agents to fight other diseases. Vaccinia virus is the prototype poxvirus and the vaccine used to eradicate smallpox. Poxvirus genes follow a cascade temporal expression pattern, categorized into...

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PMID: 40111027
DOI: 10.1128/mbio.03809-24

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