Article
Homologs of vascular endothelial growth factor are encoded by the poxvirus orf virus.
Journal of virology - 1 Jan 1994
Lyttle D J, Fraser K M, Fleming S B, Mercer A A, Robinson A J
Abstract excerpt
A gene encoding a polypeptide with homology to mammalian vascular endothelial growth factors (VEGFs) has been discovered in the genome of orf virus (OV), a parapoxvirus that affects sheep and goats and, occasionally, humans. The gene is transcribed abundantly early in infection and is found immed...
Topics
- Amino Acid Sequence
- Animals
- Base Composition
- Base Sequence
- Cattle
- Cells, Cultured
- Endothelial Growth Factors
- Genes, Viral
- Genetic Variation
- Genome, Viral
- Lymphokines
- Male
- Models, Genetic
- Molecular Sequence Data
- Multigene Family
- Orf virus
- Restriction Mapping
- Sequence Analysis, DNA