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Article

Homologs of vascular endothelial growth factor are encoded by the poxvirus orf virus.

Journal of virology - 1 Jan 1994

Lyttle D J, Fraser K M, Fleming S B, Mercer A A, Robinson A J

Abstract excerpt

A gene encoding a polypeptide with homology to mammalian vascular endothelial growth factors (VEGFs) has been discovered in the genome of orf virus (OV), a parapoxvirus that affects sheep and goats and, occasionally, humans. The gene is transcribed abundantly early in infection and is found immediately outside the inverted terminal repeat at the right end of the genome. In the NZ2 strain of OV (OV NZ2), the gene...

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Identifiers

PMID: 8254780
DOI: 10.1128/JVI.68.1.84-92.1994
PMCID: PMC236267

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Homologs of vascular endothelial growth factor are encoded by the poxvirus orf virus.PMID 8254780Read ↗

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