Article
Rates of spontaneous mutation in an archaeon from geothermal environments.
Journal of bacteriology - 1 May 1997
Jacobs K L, Grogan D W
Abstract excerpt
To estimate the efficacy of mechanisms which may prevent or repair thermal damage to DNA in thermophilic archaea, a quantitative assay of forward mutation at extremely high temperature was developed for Sulfolobus acidocaldarius, based on the selection of pyrimidine-requiring mutants resistant to...
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