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Article

Moderate frequency of BRCA1 and BRCA2 germ-line mutations in Scandinavian familial breast cancer.

American journal of human genetics - 1 May 1997

Håkansson S, Johannsson O, Johansson U, Sellberg G, Loman N, Gerdes A M, Holmberg E, Dahl N, Pandis N, Kristoffersson U, Olsson H, Borg A

Abstract excerpt

Previous studies of high-risk breast cancer families have proposed that two major breast cancer-susceptibility genes, BRCA1 and BRCA2, may account for at least two-thirds of all hereditary breast cancer. We have screened index cases from 106 Scandinavian (mainly southern Swedish) breast cancer and breast-ovarian cancer families for germ-line mutations in all coding exons of the BRCA1 and BRCA2 genes, using the...

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Source

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Identifiers

PMID: 9150154
PMCID: PMC1712420

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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