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Article

Simultaneous detection of multiple point mutations using fluorescence-coupled competitive primer extension.

BioTechniques - 1 May 1997

Fauser S, Wissinger B

Abstract excerpt

We report the development of a method for the simultaneous genotyping of several distinct nucleotide positions by means of fluorescence-coupled competitive primer extension. We demonstrate the application of this method for the simultaneous detection of three point mutations in the human mitochondrial genome, at nucleotide positions 3460, 11778 and 14484, which account for about 90% of cases with Leber's...

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Identifiers

PMID: 9149883
DOI: 10.2144/97225rr05

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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