Article
Multiplex analysis of mutations in four genes using fluorescence scanning technology.
Thrombosis research - 1 Oct 1999
Benson J M, Ellingsen D, Renshaw M A, Resler A G, Evatt B L, Hooper W C
Abstract excerpt
Multiplex analysis of genetic mutations using fluorescence scanning methodology is an accurate, efficient, and cost-effective approach to genotypic characterization. Fluorescence labeling during the synthesis of polymerase chain reaction primers allows the application of this technology to well-established protocols. We have simultaneously analyzed the four polymorphisms of factor V Leiden (G1691A), prothrombin...
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