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Article

Variable regions V13 and V3 of Saccharomyces cerevisiae contain structural features essential for normal biogenesis and stability of 5.8S and 25S rRNA.

RNA (New York, N.Y.) - 1 May 1997

Jeeninga R E, Van Delft Y, de Graaff-Vincent M, Dirks-Mulder A, Venema J, Raué H A

Abstract excerpt

The homologous ribosomal RNA species of all organisms can be folded into a common "core" secondary structure. In addition, eukaryotic rRNAs contain a large number of segments, located at fixed positions, that are highly variable in size and sequence from one organism to another. We have investigated the role of the two largest of these variable regions in Saccharomyces cerevisiae 25S rRNA, V13, and V3, by...

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PMID: 9149229
PMCID: PMC1369498

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