Article
Variable regions V13 and V3 of Saccharomyces cerevisiae contain structural features essential for normal biogenesis and stability of 5.8S and 25S rRNA.
RNA (New York, N.Y.) - 1 May 1997
Jeeninga R E, Van Delft Y, de Graaff-Vincent M, Dirks-Mulder A, Venema J, Raué H A
Abstract excerpt
The homologous ribosomal RNA species of all organisms can be folded into a common "core" secondary structure. In addition, eukaryotic rRNAs contain a large number of segments, located at fixed positions, that are highly variable in size and sequence from one organism to another. We have investiga...
Topics
- Base Sequence
- Cloning, Molecular
- DNA Mutational Analysis
- Escherichia coli
- Genetic Variation
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Nucleic Acid Conformation
- RNA Precursors
- RNA Processing, Post-Transcriptional
- RNA, Ribosomal
- RNA, Ribosomal, 5.8S
- Saccharomyces cerevisiae