Article
Induction of molecular and mechanical transformations in canine skeletal muscle by chronic neuromuscular stimulation.
Journal of muscle research and cell motility - 1 Feb 1997
Zhang K M, Wright L D, Hu P, Spratt J A, Wechsler A S, Briggs F N
Abstract excerpt
The canine latissimus dorsi was stimulated at 1 Hz via the thoracodorsal nerve for 70 days. Seven days of muscle stimulation caused muscle mass, fibre cross-sectional areas, and tetanic tensions to decrease. Fourteen days of stimulation produced marked decreases in Ca(2+)-uptake rates in a membra...
Topics
- Animals
- Calcium
- Calcium-Transporting ATPases
- Dogs
- Electric Stimulation
- Fluorescein-5-isothiocyanate
- Muscle Fibers, Fast-Twitch
- Muscle Fibers, Slow-Twitch
- Muscle, Skeletal
- Myosin Heavy Chains
- Neuromuscular Junction
- Organ Size
- Phenotype