Article
Induction of molecular and mechanical transformations in canine skeletal muscle by chronic neuromuscular stimulation.
Journal of muscle research and cell motility - 1 Feb 1997
Zhang K M, Wright L D, Hu P, Spratt J A, Wechsler A S, Briggs F N
Abstract excerpt
The canine latissimus dorsi was stimulated at 1 Hz via the thoracodorsal nerve for 70 days. Seven days of muscle stimulation caused muscle mass, fibre cross-sectional areas, and tetanic tensions to decrease. Fourteen days of stimulation produced marked decreases in Ca(2+)-uptake rates in a membrane fraction containing sarcoplasmic reticulum. At this time there was a decline in fusion frequency, but no...
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