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Article

Sex and death in the mouse: genetically delayed reproduction and senescence.

Genome - 1 Apr 1997

Biddle F G, Eden S A, Rossler J S, Eales B A

Abstract excerpt

A mammalian model of genetically postponed aging would be an important tool to test not only different mechanisms of aging but also the predictive value of various biomarkers of the aging process. Under conventional conditions, the historical strains of the laboratory mouse produce their first litter between 9 and 13 weeks of age and have a median time of death in their 2nd year. Our POSCH-2 strain, which was...

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PMID: 9134704
DOI: 10.1139/g97-032

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