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Overexpression of folate binding protein in ovarian cancers

22 Apr 1997

Abstract excerpt

The high affinity folate binding protein (FBP) is overexpressed in ovarian cancers. However, its role in the pathogenesis and biological behaviour of these neoplasms is not clearly understood. Using the monoclonal antibody (MAb) MOv 18 and cytofluorimetric analysis, we investigated FBP expression in frozen neoplastic tissues from 136 patients diagnosed with epithelial ovarian cancer. FBP values were compared with...

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PMID: 9133455
DOI: 10.1002/(sici)1097-0215(19970422)74:2<193::aid-ijc10>3.0.co;2-f

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