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Folate Receptor-Positive Gynecological Cancer Cells: In Vitro and In Vivo Characterization

15 Aug 2017

Abstract excerpt

The folate receptor (FR) is expressed in a variety of gynecological cancer types. It has been widely used for tumor targeting with folic acid conjugates of diagnostic and therapeutic probes. The cervical KB tumor cells have evolved as the standard model for preclinical investigations of folate-based (radio) conjugates. In this study, a panel of FR-expressing human cancer cell lines-including cervical (HeLa, KB,...

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PMID: 28809784
DOI: 10.3390/ph10030072

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