Article
PIBF (progesterone induced blocking factor) is overexpressed in highly proliferating cells and associated with the centrosome
20 May 2004
Abstract excerpt
PIBF was previously identified as a 34 kDa immunomodulatory molecule secreted by pregnancy lymphocytes and is thought to play a crucial role in preventing rejection of the embryo by the maternal immune response. Recent data suggested that PIBF protein was also expressed by the progesterone receptor (PR) positive MCF-7 breast tumor cell line. Therefore our study was designed to analyze the expression of PIBF in...
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