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Article

Development of a simple restriction fragment length polymorphism (RFLP) based assay for HCV genotyping and comparative analysis with genotyping and serotyping tests.

Journal of virological methods - 1 Apr 1997

Thiers V, Jaffredo F, Tuveri R, Chodan N, Bréchot C

Abstract excerpt

The distribution between the different hepatitis C virus genotypes and subtypes has potentially important clinical and epidemiological implications. With this view a simple restriction fragment length polymorphism (RFLP) based assay was developed to identify the three major genotypes, 1, 2 and 3 and distinguish subtype 1a from 1b. This RFLP test uses a combination of three restriction endonuclease digestions,...

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PMID: 9128857
DOI: 10.1016/s0166-0934(96)02162-3

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