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Article

Frequency of deletional alpha-thalassemia genotypes in a predominantly Asian-American population.

American journal of clinical pathology - 1 May 1997

Hofgärtner W T, West Keefe S F, Tait J F

Abstract excerpt

alpha-Thalassemia is prevalent among Asian-Americans. Most cases involve deletions of one or more alpha-globin genes. Parents with two-gene cis deletions can have offspring with hemoglobin Bart's hydrops fetalis or hemoglobin H disease. The diversity of deletions poses special challenges to laboratories that offer DNA-based testing for alpha-thalassemia. The purpose of this study was to determine both the...

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PMID: 9128271
DOI: 10.1093/ajcp/107.5.576

Genes

SEA

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Source receipt: pubmed, retrieved 7 Sept 2026.

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