Article
Frequency of deletional alpha-thalassemia genotypes in a predominantly Asian-American population.
American journal of clinical pathology - 1 May 1997
Hofgärtner W T, West Keefe S F, Tait J F
Abstract excerpt
alpha-Thalassemia is prevalent among Asian-Americans. Most cases involve deletions of one or more alpha-globin genes. Parents with two-gene cis deletions can have offspring with hemoglobin Bart's hydrops fetalis or hemoglobin H disease. The diversity of deletions poses special challenges to labor...
Topics
- Anemia
- Asia
- Asian
- Blotting, Southern
- DNA Mutational Analysis
- Female
- Gene Deletion
- Gene Frequency
- Genotype
- Humans
- Male
- Pregnancy
- Washington
- alpha-Thalassemia