Article
Rapid confirmation of Southeast Asian and Filipino alpha-thalassemia genotypes from newborn screening specimens.
American journal of hematology - 1 Sept 2002
Bhardwaj Urvashi, Zhang Yao-Hua, Blackburn William, McCabe Linda L, McCabe Edward R B
Abstract excerpt
Alpha(+)-thalassemia (-alpha) is prevalent throughout tropical and subtropical regions of world, whereas alpha(0)-thalassemia (--) occurs at higher frequency in Southeast Asia. Homozygosity for the alpha(0)-thalassemia deletion (--/--) is a serious health problem in Southeast Asia and the Philippines and is responsible for the majority of hydrops fetalis in this region. Asian immigration in United States has...
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