Heterogeneity in the expression of Fc gammaRIII in morphologically mature granulocytes from patients with chronic myeloid leukemia.

doi:10.1016/s0145-2126(96)00118-x

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Article

Heterogeneity in the expression of Fc gammaRIII in morphologically mature granulocytes from patients with chronic myeloid leukemia.

Leukemia research - 1 Mar 1997

Kant A M, Advani S H, Zingde S M

Abstract excerpt

Morphologically mature granulocytes from patients with chronic myeloid leukemia exhibit a defect in receptor mediated endocytosis of FITC-conjugated heat-aggregated IgG. In our earlier studies, we have shown that transcripts for Fc gammaRII and Fc gammaRIII are lowered in CML granulocytes, while...

Topics

Antigens, Neoplasm
Granulocytes
Humans
In Situ Hybridization
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Mutation
RNA, Messenger
Receptors, IgG

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