Article
Strong association between microsatellites and an HLA-B, DR haplotype (B18-DR3): implication for microsatellite evolution.
Immunogenetics - 1 Jan 1996
Crouau-Roy B, Bouzekri N, Carcassi C, Clayton J, Contu L, Cambon-Thomsen A
Abstract excerpt
The HLA haplotype B18-DR3 has a widespread geographical distribution, but has its greatest frequencies in Southern Europe, probably vestigial of the earliest populations of this region, particularly in the Pays Basque and Sardinia. This haplotype is of medical significance, being that most implicated as a factor of risk in insulin-dependent diabetes mellitus. In this study, the closely linked microsatellite...
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