Article
Cytogenetic abnormalities and microsatellite instability in endometrial adenocarcinoma.
Cancer genetics and cytogenetics - 1 Apr 1997
Sirchia S M, Pariani S, Rossella F, Garagiola I, De Andreis C, Bulfamante G, Zannoni E, Radaelli U, Simoni G
Abstract excerpt
Recently various authors described a new mechanism involved in the genesis of some tumors, which is characterized by a tendency for replication mistakes and by genomic instability of microsatellite repeats. This instability can be revealed through the shift in the electrophoretic mobility of the analyzed fragments, which is due to a different number of repeat units. This phenomenon is widely documented in...
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