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Article

Quantitative trait loci controlling refractoriness to Plasmodium falciparum in natural Anopheles gambiae mosquitoes from a malaria-endemic region in western Kenya.

Genetics - 1 May 2006

Menge David M, Zhong Daibin, Guda Tom, Gouagna Louis, Githure John, Beier John, Yan Guiyun

Abstract excerpt

Natural anopheline populations exhibit much variation in ability to support malaria parasite development, but the genetic mechanisms underlying this variation are not clear. Previous studies in Mali, West Africa, identified two quantitative trait loci (QTL) in Anopheles gambiae mosquitoes that confer refractoriness (failure of oocyst development in mosquito midguts) to natural Plasmodium falciparum parasites. We...

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Identifiers

PMID: 16510784
DOI: 10.1534/genetics.105.055129
PMCID: PMC1461423

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