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Article

How do cystic fibrosis transmembrane conductance regulator mutations produce lung disease?

Current opinion in pulmonary medicine - 1 Nov 1995

Pilewski J M, Frizzell R A

Abstract excerpt

In recent years, several functions of the cystic fibrosis transmembrane conductance regulator have been discovered, yet the pathophysiology of the pulmonary disease in cystic fibrosis remains unclear. At the cellular level, functions of this protein include regulation of chloride and sodium transport at the cell membrane and in intracellular organelles, regulation of protein trafficking, and posttranslational...

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PMID: 9363079
DOI: 10.1097/00063198-199511000-00002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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