How do cystic fibrosis transmembrane conductance regulator mutations produce lung disease?

doi:10.1097/00063198-199511000-00002

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Article

How do cystic fibrosis transmembrane conductance regulator mutations produce lung disease?

Current opinion in pulmonary medicine - 1 Nov 1995

Pilewski J M, Frizzell R A

Abstract excerpt

In recent years, several functions of the cystic fibrosis transmembrane conductance regulator have been discovered, yet the pathophysiology of the pulmonary disease in cystic fibrosis remains unclear. At the cellular level, functions of this protein include regulation of chloride and sodium trans...

Topics

Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Humans
Lung Diseases
Mutation

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