Article
Linkage and association of insulin gene VNTR regulatory polymorphism with polycystic ovary syndrome.
Lancet (London, England) - 5 Apr 1997
Waterworth D M, Bennett S T, Gharani N, McCarthy M I, Hague S, Batty S, Conway G S, White D, Todd J A, Franks S, Williamson R
Abstract excerpt
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting up to 10% of women of reproductive age. Women with anovulatory PCOS have hyperinsulinaemia, insulin resistance, and dyslipidaemia, and the syndrome is associated with greatly increased risks of non-insulin-dependent diabetes mellitus and cardiovascular disease and it often clusters in families. The VNTR (variable number of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.