Article
No association of the insulin gene VNTR polymorphism with polycystic ovary syndrome in a Han Chinese population.
Reproductive biology and endocrinology : RB&E - 1 Dec 2009
Xu Yuping, Wei Zhaolian, Zhang Zhiguo, Xing Qiong, Hu Pin, Zhang Xiaohui, Gao Guihua, Wang Yong, Gao Qian, Yi Long, Cao Yunxia
Abstract excerpt
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine disorder associated with an increased risk of type II diabetes mellitus. The results of previous research about the association of the VNTR polymorphism in 5-prime flanking region of the insulin (INS) gene with PCOS have been inconsistent. The present study was to investigate the association of the INS-VNTR polymorphism with PCOS in a Han Chinese...
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