The carboxyl-terminal region of factor IX is essential for its secretion.

doi:10.1021/bi962002v

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Article

The carboxyl-terminal region of factor IX is essential for its secretion.

Biochemistry - 8 Apr 1997

Kurachi S, Pantazatos D P, Kurachi K

Abstract excerpt

The carboxyl-terminal region of factor IX (residues 403-415) contains several natural mutations which result in mild to severe forms of hemophilia B. A battery of factor IX minigene expression vectors carrying various mutations in the C-terminal region were constructed and studied by transient ex...

Topics

Animals
Blood Coagulation
Blotting, Northern
Cyanogen Bromide
Cysteine Endopeptidases
Epitopes
Factor IX
Genetic Vectors
Hemophilia B
Humans
Liver Neoplasms, Experimental
Multienzyme Complexes
Mutagenesis, Site-Directed
Mutation
Oligodeoxyribonucleotides
Peptide Fragments
Protease Inhibitors
Proteasome Endopeptidase Complex

Source

Open in PubMed

Identifiers

PMID: 9100030
DOI: 10.1021/bi962002v

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9100030-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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