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Article

The carboxyl-terminal region of factor IX is essential for its secretion.

Biochemistry - 8 Apr 1997

Kurachi S, Pantazatos D P, Kurachi K

Abstract excerpt

The carboxyl-terminal region of factor IX (residues 403-415) contains several natural mutations which result in mild to severe forms of hemophilia B. A battery of factor IX minigene expression vectors carrying various mutations in the C-terminal region were constructed and studied by transient expression assay using HepG2 cells. Mutations included in this study are Y404P, I408N, T412N, T412S, T415G, T415S, T415L,...

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Identifiers

PMID: 9100030
DOI: 10.1021/bi962002v

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The carboxyl-terminal region of factor IX is essential for its secretion.PMID 9100030Read ↗

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