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Bovine Herpesvirus 1 Downregulates the Expression of Bovine MHC Class I Molecules

1 Jan 1997

Abstract excerpt

The mechanism of immunosuppression induced by bovine herpesvirus 1 (BHV-1) was investigated by studying the effects of the virus on the expression of major histocompatibility complex (MHC) class I molecules. After infection with the virus, the expression of class I molecules was detected by flow cytometry and pulse-chase analysis. A selective downregulation of expression of class I molecules was seen in the...

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PMID: 9095529
DOI: 10.1089/vim.1997.10.21

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