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A Mutation in the Latency-Related Gene of Bovine Herpesvirus 1 Leads to Impaired Ocular Shedding in Acutely Infected Calves

15 Sept 2001

Abstract excerpt

Bovine herpesvirus 1 (BHV-1) is an important pathogen of cattle, and infection is usually initiated in the ocular or nasal cavity. Like other alphaherpesviruses, BHV-1 establishes latency in sensory neurons but has the potential of reactivating from latency and spreading. The only abundant viral transcript expressed during latency is the latency-related (LR) RNA, which is alternatively spliced in trigeminal...

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Identifiers

PMID: 11507196
DOI: 10.1128/jvi.75.18.8507-8515.2001

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A Mutation in the Latency-Related Gene of Bovine Herpesvirus 1 Leads to Impaired Ocular Shedding in Acutely Infected CalvesPMID 11507196Read ↗

A mutation in the latency-related gene of bovine herpesvirus 1 disrupts the latency reactivation cycle in calves.Semantic proximity Read ↗

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