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Article

Down-regulation of MHC class I expression by equine herpesvirus-1.

The Journal of general virology - 1 Feb 2003

Rappocciolo Giovanna, Birch James, Ellis Shirley A

Abstract excerpt

There is good evidence that cytotoxic T lymphocytes play an important role in the clearance of equine herpesvirus-1 (EHV1) in horses. We have demonstrated that, in common with other alphaherpesviruses, EHV1 infection can lead to dramatic down-regulation of MHC class I expression at the cell surface, a common strategy for pathogen evasion of the host immune response. This down-regulation is specific for MHC class...

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Source

Identifiers

PMID: 12560560
DOI: 10.1099/vir.0.18612-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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