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Article

oroshigane, a new segment polarity gene of Drosophila melanogaster, functions in hedgehog signal transduction.

Genetics - 1 Apr 1997

Epps J L, Jones J B, Tanda S

Abstract excerpt

Here we describe a new segment polarity gene of Drosophila melanogaster, oroshigane (oro). Identified as a dominant enhancer of Bar (B), oro is also recessive embryonic lethal, and homozygous oro embryos show variable substitution of naked cuticle with denticles. These patterns are distinctly similar to those of hedgehog (hh) and wingless (wg) embryos, which indicates that oro functions in determining embryonic...

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Identifiers

PMID: 9093856
DOI: 10.1093/genetics/145.4.1041
PMCID: PMC1207874

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