Article
Electrogenic sulfate/chloride exchange in Xenopus oocytes mediated by murine AE1 E699Q.
The Journal of general physiology - 1 Mar 1997
Chernova M N, Jiang L, Crest M, Hand M, Vandorpe D H, Strange K, Alper S L
Abstract excerpt
Functional evaluation of chemically modified human erythrocytes has led to the proposal that amino acid residue E681 of the band 3 anion exchanger AE1 lies on the anion translocation pathway and is a proton carrier required for H+/SO4(2-) cotransport. We have tested in Xenopus oocytes the functional consequences of mutations in the corresponding residue E699 of mouse AE1. Most mutations tested abolished...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.