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Pathogenesis of Langerhans Cell Histiocytosis

20 Aug 2012

Abstract excerpt

Langerhans cell histiocytosis (LCH) combines in one nosological category a group of diseases that have widely disparate clinical manifestations but are all characterized by accumulation of proliferating cells with surface markers and ultrastructural features similar to cutaneous Langerhans cells (LCs). Despite this unified nosology, important questions about LCH remain unanswered. First, despite having phenotypic...

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PMID: 22906202
DOI: 10.1146/annurev-pathol-020712-163959

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