Article
Isolation and long-term culture of gallbladder epithelial cells from wild-type and CF mice.
In vitro cellular & developmental biology. Animal - 1 Feb 1997
Kuver R, Savard C, Nguyen T D, Osborne W R, Lee S P
Abstract excerpt
Mice with targeted disruption of the cftr gene show pathophysiologic changes in the gallbladder, which correlate with hepatobiliary disease seen in cystic fibrosis patients. As gallbladder epithelium secretes mucin, and as this epithelium consists of a relatively homogenous cell type, study of CFTR function in these cells would be beneficial to delineate the complex cellular functions of this protein. The size...
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